(7) Tue 11 Nov 97 20:54 By: Martin Goldberg To: David Ragland Re: chimpanzee St: ------------------------------------------------------------------------------ @EID:ace9 236ba6c0 @MSGID: 1:124/9005.221 83850457 Fundy, Here is the molecualr biological evidence i promised you for the occurance or evolution. It is the DNA sequence for human and chimp hemoglobin beta chain. It is 98% identical. I wonder why that is. Read it and weep and then reply. I enjoy getting posts from beaten men. gb|U01317|HUMHBB Human beta globin region on chromosome 11. Length = 73,308 Plus Strand HSPs: Score = 6559 (1812.4 bits), Expect = 0.0, Sum P(12) = 0.0 Identities = 1327/1346 (98%), Positives = 1327/1346 (98%), Strand = Plus / Plus Query: 1 GAATTCCTGGTTGGCTGATGGAAAGATGGGGCAGCTGTTCACTGGTACGCAGGGTTTTAG 60 GAATTCCTGGTTGGCTGATGGAAAGATGGGGCAACTGTTCACTGGTACGCAGGGTTTTAG 43782 ATGTATGTACCTAAGGATATGAGGTATGGCAATGAACAGAAATTCTTTTGGGAATGAGTT 120 ATGTATGTACCTAAGGATATGAGGTATGGCAATGAACAGAAATTCTTTTGGGAATGAGTT 43842 TTAGGGCCATTAAAGGACATGACCTGAAGTTTGCTCTCAGGCCAGTCCCCAGAACTCAAT 180 TTAGGGCCATTAAAGGACATGACCTGAAGTTTCCTCTGAGGCCAGTCCCCACAACTCAAT 43902 ATAAATGTGTTTCCTGCATATAGTCAAAGTTGCCACTTCTTTTTCTTCATATCATCGATC 240 ATAAATGTGTTTCCTGCATATAGTCAAAGTTGCCACTTCTTTTTCTTCATATCATCGATC 43962 TCTGCTCTTAAAGATAATCTTGGTTTTGCCTCAAACTGTTTGTCACTACAAACTTTCCCC 300 TCTGCTCTTAAAGATAATCTTGGTTTTGCCTCAAACTGTTTGTCACTACAAACTTTCCCC 44022 ATATTCCTAAGTAAAACAGATAACTGCCTCTCAACTATATCAAGTAGACTAAAATATTGT 360 ATGTTCCTAAGTAAAACAGGTAACTGCCTCTCAACTATATCAAGTAGACTAAAATATTGT 44082 GTCTCTAATATCAGAGATTCAGCTTTAATATATTGGGTTTAACTCTTTGAAATTTAGAGT 420 GTCTCTAATATCAGAAATTCAGCTTTAATATATTGGGTTTAACTCTTTGAAATTTAGAGT 44142 CTCCTTGAAATACACATGGGGGTGATTTCCTAAACTTTATTTCTTGTAAGGATTTATCTC 480 CTCCTTGAAATACACATGGGGGTGATTTCCTAAACTTTATTTCTTGTAAGGATTTATCTC 44202 AGGGGTAACACACAAACCAGCGTCCTGAACCTCTAAGTATGAGGACAGTAAGCCTTAAGA 540 AGGGGTAACACACAAACCAGCATCCTGAACCTCTAAGTATGAGGACAGTAAGCCTTAAGA 44262 ATATAAAATAAACTGTTCTTCTCTCTGCCGGTGGAAGTGTGCCCTGTCTATTCCTGAAAT 600 ATATAAAATAAACTGTTCTTCTCTCTGCCGGTGGAAGTGTGCCCTGTCTATTCCTGAAAT 44322 TGCTTGTTTGAGACGCGTGAGACGTGCAGCACATGAGACACGTGCAGCCGCCTGTGGAAT 660 TGCTTGTTTGAGACGCATGAGACGTGCAGCACATGAGACACGTGCAGCAGCCTGTGGAAT 44382 ATTGTCAGTGAAGAATGTCTCTGCCTGATTAGATATAAAGACAAGTTAAACACAGCATTA 720 ATTGTCAGTGAAGAATGTCTTTGCCTGATTAGATATAAAGACAAGTTAAACACAGCATTA 44442 GACTATAGATCAAGCCTGTGCCAGACACAAATGACCTAATGCCCAGCACGGGCCATGGAA 780 GACTATAGATCAAGCCTGTGCCAGACACAAATGACCTAATGCCCAGCACGGGCCACGGAA 44502 TCTCCTATCCTCTTGCTTGAACAGAGCAGCACACTTCTCCCCCAACACTATTAGATGTTC 840 TCTCCTATCCTCTTGCTTGAACAGAGCAGCACACTTCTCCCCCAACACTATTAGATGTTC 44562 TGGCATAATTTTGTAGATATGTAGGATTTGACATGGACTATTGTTCAATGATTCAGAGGA 44622 TGGCATAATTTTGTATATATGTAGGATTTGACATGGACTATTGTTCAATGATTCAGAGGA AATCTCTTTTGTTCAGATAAGTACACTGACTACTAAATGGATTAAAAAACACAGTAATAA 960 AATCTCCTTTGTTCAGATAAGTACACTGACTACTAAATGGATTAAAAAACACAGTAATAA 44682 AACCCAGTTTTCCCCTTACTTCCCTAGTTTGTTTCTTATTCTGCTTTCTTCCAAATTGAT 1020 AACCCAGTTTTCCCCTTACTTCCCTAGTTTGTTTCTTATTCTGCTTTCTTCCAAGTTGAT 44742 TITLE Isolation and nucleotide sequence analysis of the beta-type globin pseudogene from human, gorilla and chimpanzee JOURNAL J. Mol. Biol. 180, 767-784 (1984) MEDLINE 85134894 REFERENCE 2 (bases 1606 to 3752) AUTHORS Koop,B.F., Goodman,M., Xu,P., Chan,K. and Slightom,J.L. TITLE Primate eta-globin DNA sequences and man's place among the great apes JOURNAL Nature 319, 234-238 (1986) MEDLINE 86118664 REFERENCE 3 (bases 1 to 7025) AUTHORS Miyamoto,M.M., Slightom,J.L. and Goodman,M. TITLE Phylogenetic relations of humans and African apes from DNA sequences in the pseudo-eta-globin region JOURNAL Science 238, 369-373 (1987) MEDLINE 88018021 COMMENT [3] revises [1];[2]. Computer-readable sequence for REFERENCE 1 (bases 62409 to 62631; 63482 to 63610) AUTHORS Marotta,C.A., Forget,B.G., Weissman,S.M., Verma,I.M., McCaffrey,R.P. and Baltimore,D. TITLE Nucleotide sequences of human globin messenger RNA JOURNAL Proc. Natl. Acad. Sci. U.S.A. 71, 2300-2304 (1974) MEDLINE 74275150 REFERENCE 2 (bases 63602 to 63646) AUTHORS Forget,B.G., Marotta,C.A., Weissman,S.M. and Cohen-Solal,M.M. TITLE Nucleotide sequences of the 3'-terminal untranslated region of messenger RNA for human beta globin chain JOURNAL Proc. Natl. Acad. Sci. U.S.A. 72, 3614-3618 (1975) MEDLINE 76053173 REFERENCE 3 (bases 63593 to 63626) AUTHORS Proudfoot,N.J. and Brownlee,G.G. TITLE Nucleotide sequences of globin messenger RNA JOURNAL Br. Med. Bull. 32, 251-256 (1976) MEDLINE 77022845 REFERENCE 4 (bases 63673 to 63743) AUTHORS Proudfoot,N.J. and Longley,J.I. TITLE The 3' terminal sequences of human alpha and beta globin messenger RNAs: Comparison with rabbit globin messenger RNA JOURNAL Cell 9, 733-746 (1976) MEDLINE 77114153 REFERENCE 5 (sites) AUTHORS Proudfoot,N.J. and Brownlee,G.G. TITLE Non-coding region sequences in eukaryotic messenger RNA JOURNAL Nature 263, 211-214 (1976) MEDLINE 76267786 REFERENCE 6 (bases 63596 to 63743) AUTHORS Proudfoot,N.J. TITLE Complete 3' noncoding region sequences of rabbit and human beta-globin messenger RNA's JOURNAL Cell 10, 559-570 (1977) MEDLINE 77183598 REFERENCE 7 (bases 62137 to 62193) AUTHORS Baralle,F.E. TITLE Complete nucleotide sequence of the 5' noncoding region of human alpha- and beta-globin mRNA JOURNAL Cell 12, 1085-1095 (1977) MEDLINE 78082246 REFERENCE 8 (sites) AUTHORS Marotta,C.A., Forget,B.G., Cohen-Solal,M.M., Wilson,J.T. and Weissman,S.M. TITLE Human beta-globin messenger RNA: I. Nucleotide sequences derived from complementary RNA JOURNAL J. Biol. Chem. 252, 5019-5031 (1977) MEDLINE 77207122 REFERENCE 9 (bases 62187 to 63610) AUTHORS Cohen-Solal,M.M., Forget,B.G., Prensky,W., Marotta,C.A. and Weissman,S.M. TITLE Human beta-globin messenger RNA: II. Nucleotide sequences derived from 125-I-labeled globin messenger RNA JOURNAL J. Biol. Chem. 252, 5032-5039 (1977) MEDLINE 77207123 REFERENCE 10 (bases 54790 to 54881; 62409 to 62631; 63482 to 63715) AUTHORS Marotta,C.A., Wilson,J.T., Forget,B.G. and Weissman,S.M. TITLE Human beta-globin messenger RNA. III. Nucleotide sequences derived from complementary DNA JOURNAL J. Biol. Chem. 252, 5040-5053 (1977) MEDLINE 77207124 REFERENCE 11 (bases 62137 to 62189) AUTHORS Chang,J.C., Temple,G.F., Poon,R., Neumann,K.H. and Kan,Y.W. TITLE The nucleotide sequences of the untranslated 5' regions of human alpha- and beta-globin mRNAs JOURNAL Proc. Natl. Acad. Sci. U.S.A. 74, 5145-5149 (1977) MEDLINE 78053067 REFERENCE 12 (bases 56103 to 56184) AUTHORS Lawn,R.M., Fritsch,E.F., Parker,R.C., Blake,G. and Maniatis,T. TITLE The isolation and characterization of linked delta- and beta-globin genes from a library of human DNA JOURNAL Cell 15, 1157-1174 (1978) MEDLINE 79084172 REFERENCE 13 (bases 35854 to 35946; 63482 to 63531) AUTHORS Little,P., Curtis,P., Coutelle,C., van den Berg,J., Dalgleish,R., Malcolm,S., Courtney,M., Westaway,D. and Williamson,R. This is what I consider reasonable evidence and a decent bibliography. --- msgedsq 2.1 * Origin: Curb Your God (1:124/9005.221) SEEN-BY: 12/12 112/4 218/890 1001 270/101 353/250 396/1 3615/50 51 SEEN-BY: 3804/180 @PATH: 124/9005 1 396/1 3615/50 218/1001